TABLE 1.
Hardy-Weinberg for different SNPs in each group.
Non-infected (n = 80) | Mild COVID-19 (n = 80) | Severe COVID-19 (n = 80) | |
---|---|---|---|
HLA-DQrs7453920 (A/G) | |||
GG® | 32 (40%) | 27 (33.8%) | 11 (13.8%) |
AG | 43 (53.8%) | 45 (56.3%) | 27 (33.8%) |
AA | 5 (6.3%) | 8 (10%) | 42 (52.5%) |
HWp | p = 0.057 | p = 0.086 | p = 0.066 |
HLA-DPrs3077 (G/A) | |||
AA® | 16 (20%) | 13 (16.3%) | 2 (2.5%) |
GA | 48 (60%) | 40 (50%) | 10 (12.5%) |
GG | 16 (20%) | 27 (33.8%) | 68 (85%) |
HWp | p = 0.074 | p = 0.778 | p = 0.052 |
IFNλ4rs73555604 (C/T) | |||
TT® | 24 (30.0%) | 20 (25%) | 7 (8.8%) |
CT | 41 (51.3%) | 45 (56.3%) | 23 (28.8%) |
CC | 15 (18.8%) | 15 (18.8%) | 50 (62.5%) |
HWp | p = 0.733 | p = 0.247 | p = 0.087 |
Statistically significant at p ≤ 0.05.
HW, Hardy-Weinberg equilibrium; ®, Reference group; p, p-value for Chi square for goodness of fit.