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Dose titration of NCATS-SM7270 in mTBI mice. Means±SD of 5 mice were treated with vehicle control and 4 mice were treated with either 10, 50, or 100 μM of NCATS-SM7270. Statistically significant (*P ≤ 0.05) reductions in TBI are indicated (Kruskal-Wallis with Dunn's multiple comparison correction).
