TABLE 1.

Protein phylogenies where gram-positive bacteria are indicated as the closest prokaryotic relatives of archaebacteria^a

Protein	Fig.		Protein	Fig.
Gyrase B	6A		trpA	17A
Photolyase	6C		trpB	17Bb
EF-Tu	8A		trpC	17C
EF-G/2	8B		trpD	17D
Isoleucyl-tRNA synthetase	9B		hisC	18Cb
Tryptophanyl-tRNA synthetase	9C		hisD	18D
Tyrosyl-tRNA synthetase	9D		hisF	18Eb
Ribosomal protein L2	10A		hisH	18Gb
Ribosomal protein L11	11B		his1E	18H
Ribosomal protein L14	11C		IMP dehydrogenase	19A
Ribosomal protein L15	11D		FGAM synthetase	19B
Ribosomal protein L22	11E		Glutamyl-tRNA reductase	19C
Ribosomal protein L23	11F		trpG	17F
Ribosomal protein L30	12A		SecY	19E
Ribosomal protein S5	12B		FeMn SOD	20Ab
Ribosomal protein S9	12E		Hsp60/Tcp-1	20B
Ribosomal protein S10	12F		Glutamine synthetase	16B
Ribosomal protein S15	13C		Glutamate dehydrogenase II	15Cb
Ribosomal protein S19	13E		Argininosuccinate synthase	15D
Enolase	13F		Aspartate aminotransferase	16A
Acetyl-CoA synthetase	15A		Histidinol-P-aminotransferase	16A
Citrate synthase	15B		hisG	18Fc
Hsp70	5b		RNA polymerase A subunit	7ac

^aThis table is based on the phylogenetic trees published by Brown and Doolittle (21). The relationships indicated are observed upon excluding the eukaryotic homologs and knowing that T. maritima is a gram-positive bacterium. Figure numbers in this table refer to figures in reference 21. CA, coenzyme A; SOD, superoxide dismutase. 

^bPolyphyletic branching of archaebacteria within gram-positive bacteria. 

^cFor these genes, no sequences for gram-positive bacteria were included in the analyses.