Table 3.
Comparison of methods for detecting EAT.
Method | Index | Standard | Advantages | Disadvantages |
---|---|---|---|---|
MRI | thickness/ volumetric | the greatest amount of epicardial fat can be found at the lateral right ventricular wall, using the summation of slices method | gold standard, radiation-free, not limited by the position and orientation of the imaging planes | Costly, time-intensive |
CT imaging* | thickness/ volumetric | performed along the right ventricular anterior free wall in a single sagittal slice, ranging -190 to -30 Hounsfield units | higher spatial resolution, reproducibility, best visibility of the pericardium | Costly, radiation exposure |
Via transthoracic echocardiographic ultrasound | thickness | on the free wall of the right ventricle, normal values: around 5mm |
relatively inexpensive, widely available | linear measurement, low reproducibility |
EAT attenuation as measured by CT* | mean attenuation | EAT attenuation was calculated as mean Hounsfield units of all pixels ([-190, -30]HU) | markers of adipose tissue inflammation | |
FDG-PET/computerized tomography* | EAT inflammatory activity | analysis differences between SUV in different locations | reflect glucose metabolism of the tissue |
CT computed tomography, FDG-PET 18-fluorodeoxy glucose -positron emission tomography, SUV Maximal standardized uptake value
*no meta-analysis has yet defined normal and pathological values