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. 2023 Jan 20;14:1091807. doi: 10.3389/fmicb.2023.1091807

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Copyright © 2023 He, Fan, Shen, Gou, Zhang, Liu, Zhang, Wuri, Zhang, Liao and Geri.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A model for regulation of anti-PEDV innate immunity by butyrate. Butyrate through activation of GPR43 and NF-κB, leading interferon responses and induction of downstream antiviral genes inhibition of PEDV replication.