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. 2022 Aug 18;43(2):230–244. doi: 10.1093/asj/sjac225

Table 3.

Reduction in Symptom Number by Cohort and Visit and Presence of Cutibacterium acnes at Baseline

Cohort Parameter Visit Cutibacterium acnes P-valuea
Yes (n = 22) No (n = 28)
Cohort A 50% or more reduction in symptom number 3-6 weeks 14 (66.7) 17 (63.0) 1.0000
6 months 18 (81.8) 18 (66.7) 0.3328
80% or more reduction in symptom number 3-6 weeks 6 (28.6) 11 (40.7) 0.5442
6 months 13 (59.1) 10 (37.0) 0.1567
Cohort B 50% or more reduction in symptom number 3-6 weeks 6 (85.7) 13 (46.4) 0.0964
6 months 3 (60.0) 9 (37.5) 0.6221
80% or more reduction in symptom number 3-6 weeks 2 (28.6) 10 (35.7) 1.0000
6 months 1 (20.0) 5 (20.8) 1.0000

Values are n (%). Results are limited to patients with at least 1 reported symptom at baseline based on solicited symptoms listed on the Case Report Form. aP-value from Fisher’s exact test, testing the null hypothesis that the true percentages of patients with reduction in symptom number are equal for the 2 groups vs the alternative hypothesis that these percentages are not equal.