Table 3.
Cohort | Parameter | Visit | Cutibacterium acnes | P-valuea | |
---|---|---|---|---|---|
Yes (n = 22) | No (n = 28) | ||||
Cohort A | 50% or more reduction in symptom number | 3-6 weeks | 14 (66.7) | 17 (63.0) | 1.0000 |
6 months | 18 (81.8) | 18 (66.7) | 0.3328 | ||
80% or more reduction in symptom number | 3-6 weeks | 6 (28.6) | 11 (40.7) | 0.5442 | |
6 months | 13 (59.1) | 10 (37.0) | 0.1567 | ||
Cohort B | 50% or more reduction in symptom number | 3-6 weeks | 6 (85.7) | 13 (46.4) | 0.0964 |
6 months | 3 (60.0) | 9 (37.5) | 0.6221 | ||
80% or more reduction in symptom number | 3-6 weeks | 2 (28.6) | 10 (35.7) | 1.0000 | |
6 months | 1 (20.0) | 5 (20.8) | 1.0000 |
Values are n (%). Results are limited to patients with at least 1 reported symptom at baseline based on solicited symptoms listed on the Case Report Form. aP-value from Fisher’s exact test, testing the null hypothesis that the true percentages of patients with reduction in symptom number are equal for the 2 groups vs the alternative hypothesis that these percentages are not equal.