Table 7.
Cytokine Comparison Between Cohorts
| Cytokine | Cohort A (n = 50) | Cohort B (n = 50) | Cohort C (n = 48) |
|---|---|---|---|
| IL-5 | 5 | 3 | 4 |
| IL-13 | 8 | 0 | 1 |
| IL-2 | 2 | 0 | 0 |
| IL-6 | 9 | 8 | 3 |
| IL-9 | 4 | 1 | 0 |
| IL-10 | 2 | 0 | 0 |
| IFNγ | 9 | 4 | 1 |
| TNFα | 8 | 9 | 4 |
| IL-17A | 3 | 0 | 1 |
| IL-17F | 5 | 1 | 2 |
| IL-4 | 6 | 2 | 2 |
| IL-22 | 6 | 1 | 0 |
The table shows the number of subjects within each cohort who had above-normal levels of the respective cytokine. The number of subjects with higher levels for IL-13, IL17A, and IL-22 were significantly higher in Cohort A. TNF and IL-6 proinflammatory cytokines were higher in Cohorts A and B than in Cohort C. IL-2, IFNγ, IL-10, and IL-17F were not statistically different between cohorts. IL-4 was higher in Cohorts A and B than in Cohort C. IFN, interferon; IL, interleukin; TNF, tumor necrosis factor.