Table 3.
Proteins selected for validation.
| Direction of difference in POMS | # | Accession | Gene | Protein description | Fold changea | No. of peptidesb |
|---|---|---|---|---|---|---|
| Increased abundance | 1 | O75326 | SEMA7A | Semaphorin-7A | 1.736 | 8 |
| 2 | P16870 | CPE | Carboxypeptidase E | 1.463 | 13 | |
| 3 | Q7Z7M0 | MEGF8 | Multiple epidermal growth factor-like domains protein 8 | 1.438 | 13 | |
| 4 | Q7Z3B1 | NEGR1 | Neuronal growth regulator 1 | 1.318 | 8 | |
| 5 | Q02818 | NUCB1 | Nucleobindin-1 | 1282 | 9 |
Proteins listed in table were proteins with increased abundance in POMS with eight or more peptides significantly different belonging to one protein in discovery analyses, and finally selected for validation based on their function (CNS or immune related) and their fold change (both low and high ranges).
a
Fold change > 1 = increased abundance in POMS.
b
Number of differentially identified peptides for the same protein.