Skip to main content
. 2023 Feb 3;13(7):4623–4640. doi: 10.1039/d2ra07007c

IC50 values (μM) for the most potent NCI hits on HEK 293 cell line.

Hit IC50a (μM) Hill lope r 2 b
319 3.50 × 10−2 (±0.004) 3.7 0.93
333 6.74 (±3.55) 0.8 0.95
342 0.44 (±0.10) 2.8 0.91
Stattic 1.57 (±0.17) 2.5 0.96
Pyrimethamine 5.12 (±1.19) 1.8 0.86
a

Each value represents the average of 7 trials, values in brackets represent standard deviation of measurements.

b

The goodness of fit correlation coefficient of the dose–response curve.