IC50 values (μM) for the most potent NCI hits on HEK 293 cell line.
| Hit | IC50a (μM) | Hill lope | r 2 b |
|---|---|---|---|
| 319 | 3.50 × 10−2 (±0.004) | 3.7 | 0.93 |
| 333 | 6.74 (±3.55) | 0.8 | 0.95 |
| 342 | 0.44 (±0.10) | 2.8 | 0.91 |
| Stattic | 1.57 (±0.17) | 2.5 | 0.96 |
| Pyrimethamine | 5.12 (±1.19) | 1.8 | 0.86 |
Each value represents the average of 7 trials, values in brackets represent standard deviation of measurements.
The goodness of fit correlation coefficient of the dose–response curve.