Table 3.

Subdistribution Hazard Ratio for Waitlist Death Relative to Lung Allocation Score Group B (Pulmonary Arterial Hypertension) with Competing Risk of Transplantation

	Before 2015 Revision	After 2015 Revision
Unadjusted
Group A (COPD)	0.25 (0.21–0.30) P < 0.001	0.34 (0.26–0.44) P < 0.001
Group C (CF)	0.49 (0.41–0.59) P < 0.001	0.53 (0.39–0.72) P < 0.001
Group D (ILD)	0.51 (0.44–0.60) P < 0.001	0.74 (0.59–0.92) P = 0.006
Adjusted for age, sex, race, height, transplant type, blood type, panel reactive antibody, and ECMO at listing
Group A (COPD)	0.37 (0.31–0.45) P < 0.001	0.43 (0.33–0.57) P < 0.001
Group C (CF)	0.55 (0.45–0.68) P < 0.001	0.74 (0.53–1.03) P = 0.079
Group D (ILD)	0.77 (0.65–0.91) P = 0.002	0.95 (0.76–1.20) P = 0.683

Definition of abbreviations: CF = cystic fibrosis; COPD = chronic obstructive pulmonary disease; ECMO = extracorporeal membrane oxygenation; ILD = interstitial lung disease; LAS = lung allocation score; PAH = pulmonary arterial hypertension.

Data presented as subdistribution hazard ratio with 95% confidence interval and P value in unadjusted and adjusted competing risk regression models. LAS category A represents registrants with COPD. LAS category B represents registrants with pulmonary arterial hypertension. LAS category C represents registrants with CF. LAS category D represents registrants with ILD. The ratio represents the hazard of waitlist death in each group relative to LAS category B (PAH). Adjusted models included the following confounding and precision variables: age, sex, race, height, transplant type, ABO blood group, calculated peak panel reactive antibody, and ECMO at listing.