Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 11;1(3):pgac112. doi: 10.1093/pnasnexus/pgac112

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022. Published by Oxford University Press on behalf of National Academy of Sciences.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 4. — Synchronous fast Ca²⁺_i spikes depicted clock-independent cell–cell signaling in the SCN. (a) 1-minute recordings of GCamp6f fluorescence from SCN neurons in a same field of view. Note the occurrence of synchronous spikes in neuron subsets (delineated by three different colors). Scale bar, 100 µm. (b)–(g) Analysis of clusters of coactivity from the SCN of C57Bl/6 J (b)–(d) and Cry1-/- Cry2-/- (e)–(g) mice. (b) and (e) Global GCamp6f fluorescence (upper panel) and heat map of signal intensity from individual neurons (lower panel), recorded during 1 minute. (c), (d), (f), and (g) Extent of clusters of coactivity as a function of the density in activity (c) and (f) and time of day (d) and (g).