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. 2020 Feb 4;19(1):194–202. doi: 10.5114/aoms.2020.92830

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Copyright: © 2020 Termedia & Banach

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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Fibroblast caspase-3/7 activity after different exposure times to hemostats. Human stromal fibroblasts were exposed to hemostats placed in their medium for 5–10 (A), 30 (B), or 60 minutes (min) (C) or continuously over 24 hours (h) (D). Caspase-3 and -7 activity was analyzed as an indirect measurement for apoptosis. None of the applied hemostats caused significant apoptosis at the given exposure times (A–D). Two-way ANOVA with 2-stage step-up method of Benjamini, Krieger and Yekutieli was applied (q = 0.05, n = 5–7/experimental group)