Skip to main content
. 2023 Feb 3;13(6):1600–1620. doi: 10.1007/s13346-023-01297-9

Fig. 5.

Fig. 5

Effectiveness and safety evaluation after treatment with OVA/R848 MNs. a Effectiveness evaluation: in vivo immune response after treatment with OVA/R848 MNs. The schematic diagrams are respectively the cumulative release of OVA, the expression of IgG specifically generated by OVA after MNs treatment, and the percentage of CD8+ T cells specifically generated by OVA in the spleen. n = 5 (**P < 0.01, ****P < 0.0001). b Effectiveness evaluation: cumulative release of R848, local distribution of photothermal effect in vivo, and the change of tumor size after implantation of MNs. c Safety evaluation: dissolution of MNs, H&E staining of tumors, and important organs of mice treated with OVA and R848. Scale bar = 100 μm [135].

Copyright 2018 American Chemical Society