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. 2023 Feb 3;13(7):4678–4712. doi: 10.1039/d2ra06436g

Different techniques for antibiotics remediation, including their advantages and disadvantages.

Method Advantages Disadvantages Examples of antibiotics removed
Adsorption It is easy to operate and has low cost Product recovery usually requires expensive distillation. The capacity of the adsorbent also progressively deteriorates as you increase the number of cycles Chlortetracycline,51 sulfamethazine52
Photolysis and photocatalysis It does not lead to the formation of bromated products. It can be applied to the full-scale drinking water treatment system The penetration of light can be inhibited by turbidity. The process is also energy- and cost-intensive Tetracycline,53 ciprofloxacin54
Ozonation It enhances the effective destruction of organic matter It requires high cost Roxithromycin55
Biodegradation It is a low-cost technology and plays a critical role in pollutant degradation The rate of microbial metabolism may reduce (due to antibiotic wastewater exposure), thereby affecting the performance of biological treatment of the sewage Cephalexin,41 sulfanilamide56
Electrochemical oxidation It can be integrated with other technologies It is not widely used due to the expensive cost of electrode materials. It is also associated with low current efficiency and high energy consumption Levofloxacin57
Anaerobic treatment It is effective in removing high-strength organic compounds and breaking down refractory materials They are effective in removing non-organic pollutants from wastewater (such as nutrients and pathogens) Tylosin,58 penicillin59
Aerobic treatment It is associated with reduced odor and improved nutrient removal efficiency It requires high capital cost, high operating cost, and high maintenance requirements Tetracycline,60 Sulfamerazine46
Biofilm technology It offers operational flexibility, reduced hydraulic retention time, low space requirements, high active biomass concentration, and increased biomass residence time Operators need to be skilled in the area of biological water treatment. It also requires annual monitoring to ensure that the bacteria on the carriers are still thriving Ibuprofen,61 terramycin62
Coagulation/flocculation/sedimentation Decrease in detention time of the wastewater treatment process. They can also target different contaminants via a single system Since coagulation is an additive process, the addition of chemicals can produce a large volume of sludge that must be treated and disposed of after the treatment Sulfamerazine, sulfadimethoxine48