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. Author manuscript; available in PMC: 2023 Sep 29.
Published in final edited form as: IEEE J Solid-State Circuits. 2022 Sep 29;57(11):3243–3257. doi: 10.1109/jssc.2022.3204508

TABLE I.

Task-Specific Neural Biomarkers Integrated on the SoC

Epileptic Seizure Description
Line-Length Average of absolute temporal derivative
Hjorth Activity Variance of signal
Delta Energy Spectral energy in 1–4 Hz
Theta Energy Spectral energy in 4–8 Hz
Alpha Energy Spectral energy in 8–13 Hz
Beta Energy Spectral energy in 13–30 Hz
Low-Gamma Energy Spectral energy in 30–50 Hz
Gamma Energy Spectral energy in 50–80 Hz
High-Gamma Energy Spectral energy in 80–150 Hz
Ripple Energy Spectral energy in 150–250 Hz
Phase-Amplitude Coupling Coupling of the phase in 4–8 Hz to the amplitude envelope in 80–150 Hz
Phase Locking Value Synchronization between two-channel phases in 13–30 Hz
Parkinsonian Tremor Description

Hjorth Activity Variance of signal
Hjorth Mobility Mean frequency of signal
Hjorth Complexity Change in signal frequency
Tremor Energy Spectral energy in 1–4 Hz
Beta Energy Spectral energy in 13–30 Hz
Low-Gamma Energy Spectral energy in 30–45 Hz
Gamma Energy Spectral energy in 60–90 Hz
High-Gamma Energy Spectral energy in 100–200 Hz
Slow High-Frequency Oscillation Spectral energy in 200–300 Hz
Fast High-Frequency Oscillation Spectral energy in 300–400 Hz
High-Frequency Oscillation Ratio Ratio of the energy in 200–300 Hz to the energy in 300–400 Hz
Phase-Amplitude Coupling Coupling of the phase in 13–30 Hz to the amplitude envelope in 150–400 Hz
Finger Movement Description

Local Motor Potential Mean value of signal
Hjorth Activity Variance of signal
Hjorth Mobility Mean frequency of signal
Hjorth Complexity Change in signal frequency
Alpha Energy Spectral energy in 8–13 Hz
Beta Energy Spectral energy in 13–30 Hz
Low-Gamma Energy Spectral energy in 30–60 Hz
Gamma Energy Spectral energy in 60–100 Hz
High-Gamma Energy Spectral energy in 100–200 Hz