TABLE 5.
Overview of Lung Cancer and Pleural Mesothelioma Mortality in the Most Recent Updates of Five Cohorts Highly Exposed to Talc
| Study | Period/Location | Size | Lung Cancer N Cases; Relative Risk (CI) |
MT |
|---|---|---|---|---|
| Fordyce et al34 | 1940–1975, Vermont (United States) | 427 | 32; SMR, 1.44 (0.98–2.03) | 0 |
| Wild et al36 | 1945–1996, France | 1070 | 21; SMR, 1.23 (0.76–1.89) | 0 |
| Wild28 | 1973–1995, Austria | 542 | 7; SMR, 1.06(0.43–2.19) | 0 |
| Wergeland et al35 | 1953–2011, Norway | 390 | 21; SMR, 1.7 (0.73–1.79) | 0 |
| Cioccan et al31 | 1946–2020, Italy | 1749 | 85; SMR, 1.02 (0.82–1.27) | 0 |
| Total | 70+ years | 4178 | 166; SMR, 1.13 (0.97–1.31) | 0 |
Updates taken from Boffetta et al.37
CI, confidence interval; MT, number of mesothelioma cases observed; N, number of deaths from lung cancer; SMR, standardized mortality ratio; CI: 95 % confidence interval, MT is number of mesothelioma cases observed.