Charged residues at the subunit interface present in other family members. (A) Overlay of the subunit interface (loop F, Cys/Pro-loop, and β1 to β2 loop) from DeCLIC with other family members, nAChR (sky blue), ELIC (gray), 5-HT3AR (pink), and GABAAR (salmon) with Ca2+ ion in yellow and Ba2+ in green. The important charged residues are displayed as sticks (colored by heteroatom). (B) Display of each family member from (A) individually for clearer representation with relevant charged residues displayed as sticks and colored by heteroatom.