Table 2.

Unadjusted and Adjusted Associations of Maternal PUFA Dietary Intake (gms/day) during Pregnancy with Child Outcome

	36-mo Outcome, mean (SD)			Un-adjusted RR (95% CI)		Adjusted RR (95% CI)
	TD	ASD	Non-TD	ASD vs. TD	Non-TD v.s. TD	ASD vs. TD	Non-TD v.s. TD
Omega3 1
1st half of pregnancy	1.4 (0.7)	1.2 (0.5)	1.6 (0.9)	0.8 (0.5, 1.3)	1.2 (0.9, 1.7)	0.7 (0.4, 1.3)	1.3 (0.9, 1.8)
2nd half of pregnancy	1.5 (0.6)	1.2 (0.7)	1.5 (0.6)	0.4 (0.3, 0.8)	0.97 (0.6, 1.5)	0.6 (0.3, 0.98)	0.96 (0.6, 1.5)
Omega6 1
1st half of pregnancy	11.2 (5.4)	10.6 (3.9)	12.2 (5.3)	0.98 (0.9, 1.1)	1.0 (1.0, 1.1)	0.97 (0.9, 1.1)	1.0 (1.0, 1.1)
2nd half of pregnancy	12.3 (4.8)	10.4 (5.9)	11.9 (4.9)	0.9 (0.9, 1.0)	0.99 (0.93, 1.05)	0.97 (0.9, 1.1)	0.98 (0.9, 1.1)
LA 1
1st half of pregnancy	11.0 (5.4)	10.5 (3.9)	12.1 (5.3)	0.98 (0.9, 1.1)	1.0 (1.0, 1.1)	0.97 (0.9, 1.1)	1.0 (0.96, 1.1)
2nd half of pregnancy	12.2 (4.8)	10.3 (5.8)	11.8 (4.9)	0.9 (0.9, 1.0)	0.99 (0.9, 1.1)	0.97 (0.9, 1.1)	0.98 (0.9, 1.1)
ALA 1
1st half of pregnancy	1.2 (0.7)	1.1 (0.4)	1.4 (1.0)	0.7 (0.4, 1.3)	1.2 (0.9, 1.7)	0.6 (0.3, 1.3)	1.2 (0.8, 1.8)
2nd half of pregnancy	1.3 (0.5)	1.1 (0.6)	1.3 (0.6)	0.6 (0.3, 1.0)	1.0 (0.6, 1.7)	0.8 (0.4, 1.6)	1.0 (0.5, 1.8)

Abbreviations: TD, typical developing; ASD, autism spectrum disorders; Non-TD, nontypical development; SD: standard deviation; RR: relative risk; CI: confidence interval; LA: linoleic acid; ALA: alpha-linolenic acid; EPA: eicosapentaenoic acid; PUFA: polyunsaturated fatty acids;

¹RRs were adjusted for maternal food iron intake in the same period of pregnancy; models for EPA, DHA and AA were not converged; For the 1^st half of pregnancy, we have 82 TD, 30 ASD and 33 Non-TD; For the 2^nd half of pregnancy, we have 70 TD, 30 ASD and 31 Non-TD;