Figure 4.

Random-forest models to distinguish the gut microbiota between Alzheimer’s disease and wild-type mice during development. (a–e) Receiver operating characteristic (ROC) curves and areas under curve (AUCs) for the random-forest models with three-fold cross-validation at the one, two, three, six, and nine months of age. (f) Heatmap of the scaled Gini values in different random-forest models with respect to mouse age. Yellow and blue panels indicate bacteria with high and low Gini values, respectively.