Table 4. Demographic and clinical characteristics of patients in the nephritis and LN groups.
| Variables | Nephritis (N=108) | LN (N=100) | t/χ2 value | P-value |
| Data are presented as mean±SD, except for the data on gender and anti-Sm antibody and anti-dsDNA antibody positive rate. LN: lupus nephritis; T-Cho: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Lp(a): lipoprotein(a); ApoA: apolipoprotein A; ApoB: apolipoprotein B; A/G: albumin/globulin; BUN: blood urea nitrogen; SCr: serum creatinine; Cys-C: cystatin C; CCR: creatinine clearance rate; UA: uric acid; MA: microalbuminuria; MA/UCr: MA/urine creatinine; Fib: fibrinogen; hsCRP: high-sensitivity C-reactive protein; T4/T8: CD4+ to CD8+ T cells ratio. | ||||
| Male [n (%)] | 70 (64.82) | 13 (13.00) | 92.582 | <0.001 |
| Age (years) | 40.85±16.46 | 40.82±13.79 | −0.377 | 0.707 |
| T-Cho (mmol/L) | 4.57±1.41 | 5.07±1.55 | 1.630 | 0.106 |
| TG (mmol/L) | 1.64±0.98 | 1.96±0.96 | 1.613 | 0.110 |
| HDL-C (mmol/L) | 1.31±0.39 | 1.48±0.55 | 1.603 | 0.112 |
| LDL-C (mmol/L) | 2.60±1.06 | 2.79±1.13 | 0.856 | 0.394 |
| Lp(a) (mg/L) | 171.11±136.54 | 294.15±310.48 | 1.834 | 0.070 |
| ApoA (g/L) | 1.29±0.32 | 1.34±0.37 | 0.557 | 0.579 |
| ApoB (g/L) | 0.87±0.37 | 0.90±0.36 | 0.430 | 0.668 |
| A/G | 1.57±0.49 | 1.51±0.44 | −0.668 | 0.505 |
| BUN (mmol/L) | 7.12±6.23 | 10.16±8.48 | 2.058 | 0.042 |
| SCr (μmol/L) | 123.38±139.95 | 135.21±140.41 | 0.446 | 0.657 |
| Cys-C (mg/L) | 1.28±0.61 | 1.87±1.22 | 2.763 | 0.007 |
| CCR (mL/minute) | 77.23±29.46 | 64.85±46.88 | −1.477 | 0.142 |
| UA (μmol/L) | 354.91±124.35 | 402.37±162.85 | 1.654 | 0.100 |
| MA (mg/L) | 1083.72±1485.24 | 1819.57±3357.35 | 1.208 | 0.230 |
| MA/UCr (mg/g) | 897.33±1537.22 | 2400.72±5912.72 | 1.437 | 0.154 |
| Fib (g/L) | 3.57±1.56 | 3.40±1.23 | −0.598 | 0.551 |
| D-dimer (mg/L) | 3.86±5.94 | 3.22±6.50 | −0.352 | 0.726 |
| hsCRP (mg/L) | 19.24±35.04 | 1.45±2.30 | −4.975 | <0.001 |
| Anti-Sm antibody positive [n (%)] | 3 (2.80) | 27 (27.00) | 30.841 | <0.001 |
| Anti-dsDNA antibody positive [n (%)] | 1 (0.90) | 31 (31.00) | 28.347 | <0.001 |
| CD3+CD4+CD8− (%) | 34.32±9.74 | 32.15±8.89 | −1.267 | 0.207 |
| CD3+CD4−CD8+ (%) | 26.02±8.13 | 37.00±10.50 | 5.934 | <0.001 |
| CD3+CD4+CD8+ (%) | 0.46±0.36 | 0.84±0.91 | 2.579 | 0.011 |
| CD3+CD4−CD8− (%) | 4.76±3.99 | 3.55±2.45 | −2.177 | 0.031 |
| T4/T8 | 1.53±0.88 | 0.99±0.60 | −4.137 | <0.001 |