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a, Inhibition of COQ8ANΔ250 ATPase activity by the top candidate inhibitors (n=3 independent samples from one experiment, mean ± SD) (IC50 data are available in the supporting information). b, Top candidate inhibitor binding curves, as determined by DSF (n=3 independent samples from one experiment, mean ± SD) (Kd,app data are available in the supporting information).
