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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Psychoneuroendocrinology. 2022 Nov 24;148:105988. doi: 10.1016/j.psyneuen.2022.105988

Table 2.

Baseline levels and change over time in social support (relationship types tested separately) predicting epigenetic age (N=1912)

Horvath Hannum PhenoAge GrimAge Pace of Aging
ß b SE p ß b SE p ß b SE p ß b SE p ß b SE p
Spouse Baseline 0.02 0.51 0.36 0.159 −0.01 −0.15 0.29 0.607 −0.01 −0.18 0.37 0.630 0.00 0.05 0.21 0.822 −0.03 −0.00 0.00 0.281
Spouse Slope 0.01 323.27 766.05 0.673 0.01 332.68 609.14 0.585 −0.01 −627.43 780.40 0.422 0.01 231.82 450.81 0.607 0.04 18.47 9.63 0.055
Children Baseline 0.06 1.17 3.39 0.730 0.02 0.35 2.69 0.897 −0.06 −1.27 3.45 0.712 −0.11 −1.86 1.99 0.350 −0.40 −0.07 0.04 0.082
Children Slope 0.06 29.97 83.23 0.719 0.03 12.70 66.15 0.848 −0.07 −33.87 84.75 0.690 −0.09 −38.79 48.92 0.428 −0.39 −1.77 1.05 0.091
Friend Baseline −0.00 −0.00 0.35 0.991 0.00 0.07 0.28 0.791 0.00 0.08 0.36 0.814 0.02 0.41 0.21 0.047 0.07 0.01 0.00 0.002 *
Friend Slope 0.01 9.20 13.74 0.503 0.02 12.46 10.92 0.254 0.02 20.51 13.98 0.143 −0.01 −10.75 8.07 0.183 −0.01 −0.08 0.17 0.643
Family Baseline −0.01 −0.13 0.46 0.775 −0.02 −0.25 0.36 0.491 0.00 0.02 0.47 0.964 −0.02 −0.23 0.27 0.392 0.08 0.01 0.01 0.026
Family Slope −0.01 −5.33 11.97 0.656 0.01 3.24 9.51 0.733 0.01 5.79 12.19 0.635 −0.01 −3.14 7.04 0.656 −0.03 −0.13 0.15 0.375

Note. Standardized (ß) and unstandardized (b) estimates are displayed. Estimates are from adjusted models that include the following covariates: age, sex, race, BMI, smoking status, time between the baseline visit and the blood draw, and total number of comorbidities at baseline. Results that are p <.05 are in bold face.

*

Results that withstood Benjamini Hochberg correction for multiple comparisons.