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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: J Psychiatr Res. 2022 Dec 24;158:231–244. doi: 10.1016/j.jpsychires.2022.12.025

Table 4.

Risk/Protective Factors Examined in Relation to Anxiety Psychopathology, Ranked in Order of Strongest Risk Factor to Strongest Protective Factor

Reference Risk/Protective Factor k N Pooled Effect Size I2 AMSTAR 2 Rating GRADE Rating
Metric Estimate 95% CI p < .05 eOR
Potential risk factors (eOR > 1.00)
Fitzallen et al., 2021 Preterm birth 4 1,197 OR 2.63FE (0.87, 7.95) No 2.63 0% ★☆☆☆ ⊕ ⊕ ◯ ◯
Rönnblad et al., 2019 Job insecurity 2 7,910 OR 1.77RE (1.18, 2.65) Yes 1.77 52% ★★☆☆ ⊕ ◯ ◯ ◯
Smith et al., 2018 Doubts about actions 5 1,191 r 0.13RE (0.05, 0.20) Yes 1.61 33% ★☆☆☆ ⊕ ◯ ◯ ◯
Gong et al., 2022 Maternal severe obesity 2 1,107,912 RR 1.56FE (1.44, 1.68) Yes 1.56 0% ★★☆☆ ⊕ ⊕ ◯ ◯
Maes et al., 2019 Loneliness 10 3,995 β 0.12RE (0.04, 0.21) Yes 1.55 72% ★☆☆☆ ⊕ ◯ ◯ ◯
Jadambaa et al., 2019 Bullying victimization 20 NR RR 1.52FE (1.35, 1.72) Yes 1.52 34% ★☆☆☆ ⊕ ⊕ ◯ ◯
Smith et al., 2018 Concern over mistakes 5 1,264 r 0.11RE (0.06, 0.17) Yes 1.49 0% ★☆☆☆ ⊕ ◯ ◯ ◯
Pinquart, 2017 Parental psychological control 18 NR r 0.10RE (0.05, 0.15) Yes 1.44 0% ★☆☆☆ ⊕ ◯ ◯ ◯
Jeronimus et al., 2016 Neuroticism 9 14,646 d 0.18NR (0.06, 0.27) Yes 1.39 NR ★☆☆☆ ⊕ ◯ ◯ ◯
Gong et al., 2022 Maternal moderate obesity 2 1,107,912 RR 1.36FE (1.28, 1.44) Yes 1.36 0% ★★☆☆ ⊕ ⊕ ◯ ◯
Pinquart, 2017 Parental harsh control 2 NR r 0.08RE (−0.06, 0.21) No 1.34 0% ★☆☆☆ ⊕ ◯ ◯ ◯
Smith et al., 2018 Personal standards 4 962 r 0.08RE (0.02, 0.15) Yes 1.34 0% ★☆☆☆ ⊕ ◯ ◯ ◯
Gong et al., 2022 Maternal hypertensive disorders 3 30,517 RR 1.32RE (0.84, 1.79) No 1.32 57% ★★☆☆ ⊕ ◯ ◯ ◯
Liao et al., 2022 Peer victimization 22 NR β 0.07RE (0.05, 0.09) Yes 1.29 NR ★☆☆☆ ⊕ ◯ ◯ ◯
Smith et al., 2018 Socially prescribed perfectionism 9 2,665 r 0.04RE (0.00, 0.09) No 1.16 19% ★☆☆☆ ⊕ ◯ ◯ ◯
Pinquart, 2017 Parental behavioral control 18 NR r 0.03RE (−0.03, 0.09) No 1.12 0% ★☆☆☆ ⊕ ◯ ◯ ◯
Smith et al., 2018 Self-oriented perfectionism 8 2,363 r 0.03RE (−0.01, 0.07) No 1.12 0% ★☆☆☆ ⊕ ◯ ◯ ◯
Prieto-Fidalgo et al., 2022 Observing facet of dispositional mindfulness 13 495 β 0.03RE NR No 1.12 NR ★☆☆☆ ⊕ ◯ ◯ ◯
Twomey, 2017 Cannabis use 7 53,719 OR 1.09RE (0.97, 1.24) No 1.09 18% ★★☆☆ ⊕ ◯ ◯ ◯
Prieto-Fidalgo et al., 2022 Non-judging facet of dispositional mindfulness 14 842 β 0.01RE NR No 1.04 NR ★☆☆☆ ⊕ ◯ ◯ ◯
Potential protective factors (eOR < 1.00)
Prieto-Fidalgo et al., 2022 Describing facet of dispositional mindfulness 14 842 β −0.02RE NR No 0.93 NR ★☆☆☆ ⊕ ◯ ◯ ◯
Pinquart, 2017 Parental autonomy granting 14 NR r −0.04RE (−0.10, 0.02) No 0.86 0% ★☆☆☆ ⊕ ◯ ◯ ◯
Pinquart, 2017 Parental warmth 20 NR r −0.05RE (−0.11, 0.01) No 0.83 0% ★☆☆☆ ⊕ ◯ ◯ ◯
Khazanov & Ruscio, 2016 Positive emotionality 26 11,494 β −0.06RE (−0.09, −0.04) Yes 0.80 30% ★☆☆☆ ⊕ ◯ ◯ ◯
Prieto-Fidalgo et al., 2022 Non-reacting facet of dispositional mindfulness 13 495 β −0.09RE NR Yes 0.72 NR ★☆☆☆ ⊕ ◯ ◯ ◯
Sowislo & Orth, 2013 Self-esteem 18 3,597 β −0.10RE (−0.14, −0.06) Yes 0.69 18% ★☆☆☆ ⊕ ◯ ◯ ◯
Prieto-Fidalgo et al., 2022 Acting with awareness facet of dispositional mindfulness 17 1,175 β −0.11RE NR Yes 0.67 NR ★☆☆☆ ⊕ ◯ ◯ ◯
McDowell et al., 2019 Physical activity 3 17,725 OR 0.66RE (0.53, 0.82) Yes 0.66 62% ★★☆☆ ⊕ ⊕ ◯ ◯

Note. CI = confidence interval; eOR = equivalent odds ratio; OR = odds ratio; RR = risk ratio; RE = random effects model; FE = fixed effects model; NR = not reported.

k represents the number of samples; N represents the number of participants; I2 represents heterogeneity. AMSTAR 2 rating indicates overall methodological quality of the review, where ★☆☆☆ = critically low, ★★☆☆ = low, ★★★☆ = moderate, and ★★★★ = high. GRADE rating indicates quality of evidence for the specific risk/protective factor, where ⊕ ◯ ◯ ◯ = very low, ⊕ ⊕ ◯ ◯ = low, ⊕ ⊕ ⊕ ◯ = moderate, and ⊕ ⊕ ⊕ ⊕ = high.