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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Clin Cancer Res. 2023 Feb 1;29(3):647–658. doi: 10.1158/1078-0432.CCR-22-2355

Table 1.

Eleven Tx-expanded TCR clonotypes shared between PBMC and TIL in top 20 TCR clonotypes of post-PBMC or post-TIL

PXID CDR3 region amino_acid pre_TIL_Freq pre_TIL_Rank post_TIL_Freq post_TIL_Rank Ratio_TIL pre_PBMC_Freq pre_PBMC_Rank post_PBMC_Freq post_PBMC_Rank Ratio_PBMC

6 CASSPPSRDYVSYEQYF 1.908% 3 2.263% 1 1.186 0.31% 8 0.409% 8 1.321
15 CASSHNVYTGELFF 0.03% 537 0.728% 5 24.571 0.807% 5 0.994% 5 1.233
16 CASTRTGYPAGPHNEQFF 1.033% 4 2.401% 3 2.324 2.432% 2 3.68% 2 1.513
16 CASSLSGGGEQYF 0.302% 12 0.913% 8 3.027 0.194% 16 0.362% 10 1.871
22 CASSEAETGGYEQYF 0.111% 125 1.395% 6 12.628 0.618% 4 0.952% 2 1.54
24 CASSSLRGPEDYGYTF 0.802% 1 3.142% 1 3.919 0.679% 2 1.222% 3 1.799
24 CASSSHYPTDTQYF 0.345% 11 1.29% 7 3.736 0.287% 6 0.52% 5 1.814
24 CAISDPRDSYEQYF 0.274% 13 0.825% 11 3.007 0.192% 11 0.224% 18 1.168
24 CASSDRGDPSEPQHF 0.55% 7 0.799% 12 1.452 2.832% 1 3.549% 1 1.253
24 CASSYSTSGQETQYF 0.154% 20 0.541% 17 3.507 0.184% 12 0.505% 6 2.736
27 CASSFHAGAGNTIYF 0.668% 5 1.306% 6 1.955 0.629% 5 0.967% 6 1.537

Patient ID indicates the patient who harbors a shared expanded top TCR clonotype.

Patient 6 and 15 are non-responders and patient 16, 22, 24, and 27 are responders (in red fonts).