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. Author manuscript; available in PMC: 2024 Feb 3.
Published in final edited form as: Circ Res. 2023 Jan 4;132(3):323–338. doi: 10.1161/CIRCRESAHA.122.321586

Figure 7: Summary of the SMC sQTL and CAD GWAS colocalization and the 9p21 locus.

Figure 7:

A) Shows the colocalization summary of CAD GWAS and sQTLs signals using four different methods in SMCs. B) CDKN2B-AS1 cis-sQTL signal colocalized with the 9p21 CAD GWAS locus. C) Distribution of the percent spliced in index (PSI) values for CDKN2B-AS1 intron based on the rs10217586 genotype. D) Average expression of the 28 CDKN2B-AS1 transcripts in 151 quiescent and proliferative SMCs. The standard error of the mean is shown. The isoform structures of the two most abundant transcripts are shown. Detailed isoform structures for all transcripts are in Supplementary Figure 14.