Skip to main content
. Author manuscript; available in PMC: 2024 Feb 20.
Published in final edited form as: Free Radic Biol Med. 2023 Jan 10;196:11–21. doi: 10.1016/j.freeradbiomed.2023.01.009

Figure 3. Early maturation of mitochondrial networks in DS cells.

Figure 3.

Representative images of mitochondrial shape in DS and euploid iPSCs (A) and NPCs (B) by immunofluorescence detection of TOM20 at 60X magnification show no differences in TOM20 abundance (C). TMRE staining showed increased mitochondrial membrane potential in DS iPSCs and NPCs (D). Nuclei are stained with Hoescht. Bar = 10 μM. Results are expressed as mean +/− SEM. N = 30–40. ** = p ≤ 0.01, *** = p ≤ 0.001, **** = p ≤ 0.0001.