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. Author manuscript; available in PMC: 2024 Feb 20.
Published in final edited form as: Free Radic Biol Med. 2023 Jan 10;196:11–21. doi: 10.1016/j.freeradbiomed.2023.01.009

Table 5.

P-values obtained by two-way ANOVA show significant interaction effect from cell type and stage of differentiation on all metabolic endpoints of the Cell Mito Stress Test.

Source of Variation % of total variation P value P value summary Sig?
Non-Mito Oxygen Consumption Interaction 16.23 <0.0001 **** Yes
Day of Differentiation 15.84 <0.0001 **** Yes
Cell Type (CTL/DS) 4.623 <0.0001 **** Yes
Basal Respiration Interaction 18.88 <0.0001 **** Yes
Day of Differentiation 9.269 <0.0001 **** Yes
Cell Type (CTL/DS) 1.910 0.0063 ** Yes
Maximum Respiration Interaction 19.48 <0.0001 **** Yes
Day of Differentiation 12.73 <0.0001 **** Yes
Cell Type (CTL/DS) 5.426 <0.0001 **** Yes
ATP Production Interaction 11.58 <0.0001 **** Yes
Day of Differentiation 7.506 <0.0001 **** Yes
Cell Type (CTL/DS) 1.139 0.0469 * Yes
Proton Leak Interaction 11.19 <0.0001 **** Yes
Day of Differentiation 4.412 0.0034 ** Yes
Cell Type (CTL/DS) 2.617 0.0043 ** Yes
Coupling Efficiency Interaction 8.684 <0.0001 **** Yes
Day of Differentiation 2.226 0.0656 ns No
Cell Type (CTL/DS) 2.485 0.0047 ** Yes