Table 10.
Calculated antiproliferative activity (GI50) and cytotoxicity activity (LC50) values determined by Graph Pad Prism analysis using percent inhibition as well as percent activity respectively of the compounds.
| Compound ID | Antiproliferative (U937) GI50 (uM) | Cytotoxicity LC50 (uM) |
|---|---|---|
| 8a | 5.6 | >100 |
| 8b | 4.2 | >100 |
| 8c | 3.3 | >100 |
| 8d | 6.1 | >100 |
| 8e | >200 | >100 |
| 8f | >200 | >100 |
| 8g | 6.8 | >100 |
| 8h | 3.6 | >100 |
| 8i | 7.9 | >100 |
| 8j | 5.9 | >100 |
| 8k | 3.3 | >100 |
| 8l | 2.1 | >100 |
| 8 m | 3.9 | >100 |
| 8n | 6 | >100 |
| 8o | 1.6 | >100 |
| 8p | 3.5 | >100 |
| 8q | 5.3 | >100 |
| 8r | 3.2 | >100 |
| 8s | 3 | >100 |
| 8t | 3.6 | >100 |