Table 8.

Cytotoxicity activity, Optical density at 450 nm and percent activity was determined by LDH release assay. Triton-X100 was taken as reference positive control for cytotoxicity activity while DMSO as a diluent of these compounds was considered as a negative control where there is no cytotoxicity activity was observed.

Compound ID	OD at 450 nm at different concentrations of compounds				Percent inhibition at different concentrations of compounds
	100 μM	50 μM	25 μM	12.5 μM	100 μM	50 μM	25 μM	12.5 μM
8a	0.12	0.123	0.125	0.112	1%	2%	2%	−1%
8b	0.108	0.106	0.103	0.107	−2%	−2%	−3%	−2%
8c	0.112	0.114	0.113	0.116	−1%	0%	−1%	0%
8d	0.103	0.128	0.115	0.112	−3%	3%	0%	−1%
8e	0.111	0.111	0.099	0.101	−1%	−1%	−4%	−3%
8f	0.114	0.114	0.11	0.111	0%	0%	−1%	−1%
8g	0.118	0.122	0.117	0.118	0%	1%	0%	0%
8h	0.109	0.118	0.128	0.115	−2%	0%	3%	0%
8i	0.109	0.107	0.117	0.103	−2%	−2%	0%	−3%
8j	0.111	0.109	0.113	0.115	−1%	−2%	−1%	0%
8k	0.122	0.113	0.114	0.117	4%	−1%	0%	0%
8l	0.123	0.114	0.112	0.112	2%	0%	−1%	−1%
8m	0.117	0.119	0.122	0.113	0%	1%	1%	−1%
8n	0.113	0.119	0.111	0.117	−1%	1%	−1%	0%
8o	0.097	0.107	0.105	0.115	−4%	−2%	−2%	0%
8p	0.115	0.115	0.11	0.117	0%	0%	−1%	0%
8q	0.113	0.117	0.111	0.108	−1%	0%	−1%	−2%
8r	0.109	0.12	0.111	0.113	−2%	1%	−1%	−1%
8s	0.114	0.112	0.115	0.136	0%	−1%	0%	4%
8t	0.107	0.125	0.11	0.112	−2%	2%	−1%	−1%
Positive control (Triton-X100, 0.1%)	0.595	0.587	0.545	0.557	100%
Negative control, DMSO	0.11	0.132	0.133	0.109	0%