Table 9.

Antiproliferative activity RLU count and percent inhibition determined by Cell Titer Glo assay. Mitomycin C was taken as reference positive control for antiproliferative activity while DMSO as a diluent of these compounds was considered as a negative control where there is no antiproliferative activity was observed.

Compound ID	RLU at different concentrations of compounds				Percent inhibition at different concentrations of compounds
	200 μM	100 μM	50 μM	25 μM	200 μM	100 μM	50 μM	25 μM
8a	114	87	1204	1205	100%	102%	28%	28%
8b	101	93	964	1015	101%	102%	44%	41%
8c	95	93	677	1069	101%	102%	63%	37%
8d	94	109	1263	1401	101%	100%	24%	15%
8e	108	732	956	935	101%	59%	45%	46%
8f	119	1150	1079	1109	100%	32%	36%	34%
8g	109	284	1249	1357	100%	89%	25%	18%
8h	123	145	420	1378	100%	98%	80%	17%
8i	99	423	1060	1213	101%	80%	38%	28%
8j	95	484	1042	1807	101%	76%	39%	−12%
8k	85	106	509	1147	102%	101%	74%	32%
8l	87	104	174	680	102%	101%	96%	63%
8m	100	125	892	1039	101%	99%	49%	39%
8n	104	104	1138	1212	101%	101%	33%	28%
8o	93	79	463	838	102%	102%	77%	52%
8p	82	98	721	1075	102%	101%	60%	37%
8q	89	84	955	1231	102%	102%	45%	26%
8r	105	119	359	1225	101%	100%	84%	27%
8s	81	93	666	1023	102%	102%	64%	40%
8t	108	90	645	1132	101%	102%	65%	33%
Positive control (Mitomycin C, 10 μM)	142	143	139	140	100%
Negative control, DMSO	1985	1651	1758	1507	0%