Fig. 6.

Metabolite levels in global white matter (WM) in recovered patients vs. all controls. Boxplots displaying 1st, 2nd (median), and 3rd quartiles (box), ±95% (whiskers), and means (●) of Cho, Cr, mI, and NAA distributions within frontal, temporal, parietal, and occipital lobe WM between GOSE-defined, functionally recovered mTBI patients and all controls. Note an absence of statistically significant group differences (wLS ANCOVA, p ≥ 0.05) across all metabolites and all lobes. Abbreviations: wLS ANCOVA, weighted least squares analysis of covariance; GOSE, Glasgow Outcome Scale – Extended.