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. 2022 Nov 17;396(3):485–498. doi: 10.1007/s00210-022-02322-3

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Fig. 3 — The effect of rivastigmine and/or leflunomide in the probe test of the Morris water maze test in AlCl₃-induced AD in rats. A Time spent in the target quadrant for rats in the treatment protocol. B Time spent in target quadrant for rats in the prophylaxis protocol. C Latency time (treatment protocol). D Latency time of (prophylaxis protocol). Riva, rivastigmine; Lef, leflunomide. Data are presented as mean ± SD (n = 6) and tested with one-way ANOVA followed by the Tukey post hoc test using GraphPad Prism (v.8). Significant changes are reported at p < 0.05. *Significance relative to the control group. #Significance relative to the AlCl₃ group