. 2022 Apr 13;201(3):1301–1316. doi: 10.1007/s12011-022-03228-0

Table 3.

Effect of HBEO and HBEON on serum biochemical parameters in rats treated with TiO₂-NPs

Groups parameter	Control	HBEO	HBEON	TiO₂-NPs	TiO₂-NPs + HBEO	TiO₂-NPs + HBEON
ALT (U/L)	44.23 ± 1.06^a	44.58 ± 0.56^a	42.93 ± 1.03^b	86.41 ± 2.27^c	62.19 ± 1.81^d	52.37 ± 0.43^e
AST (U/L)	145.11 ± 1.38^a	145.38 ± 0.71^a	139.17 ± 2.86^b	204.51 ± 2.38^c	159.96 ± 1.51^d	159.71 ± 1.06^d
Alb (g/dl)	2.84 ± 0.03^a	2.55 ± 0.10^b	2.88 ± 0.04^a	1.14 ± 0.03^c	2.21 ± 0.07^d	2.03 ± 0.05^e
TP (g/dl)	6.26 ± 0.18^a	6.26 ± 0.10^a	6.82 ± 0.05^b	5.22 ± 0.24^c	5.46 ± 0.09^d	6.09 ± 0.08^a
T.BIL (g/dl)	0.89 ± 0.02^a	0.83 ± 0.02^a	0.80 ± 0.02^a	1.54 ± 0.21^a	1.13 ± 0.02^a	0.95 ± 0.04^a
D.BIL (g/dl)	0.19 ± 0.02^a	0.21 ± 0.01^a	0.22 ± 0.01^a	0.38 ± 0.02^c	0.30 ± 0.01^d	0.28 ± 0.02^d
Creatinine (g/dl)	1.14 ± 0.03^a	0.85 ± 0.04^ab	0.86 ± 0.03^b	2.52 ± 0.11^c	1.94 ± 0.02^d	1.81 ± 0.04^e
Uric acid (mg/dl)	2.26 ± 0.21^a	1.46 ± 0.07^b	1.46 ± 0.06^b	4.17 ± 0.24^c	2.59 ± 0.09^d	2.47 ± 0.10^e
Urea (mg/dl)	56.21 ± 1.38^a	53.44 ± 0.41^a	52.31 ± 0.43^a	81.32 ± 1.51^b	70.32 ± 0.78^c	59.85 ± 0.57^d

Within each column, means superscript with different letters are significantly different (p < 005)