Table 4.

Diagnostic value of miRNAs and MHR before PCI by ROC curve analysis

Index	AUC	95% CI	Specificity (%)	Sensitivity (%)	Youden index	Cut-off
MHR	0.766	0.641–0.864	63.60	80	0.436	> 0.343
miR-486-5p	0.669	0.528–0.810	70.00	59.10	0.291	≤ 0.065
miR-451a	0.823	0.706–0.908	81.80	82.50	0.643	> 0.062
miR-21-5p	0.660	0.529–0.776	45.50	82.50	0.280	≤ 0.026
MHR + miR-451a	0.915	0.844–0.985	77.30	92.50	0.698	–
miR-486-5p + miR-451a + miR-21-5p	0.893	0.817–0.969	95.50	72.50	0.680	–
MHR + miR-486-5p + miR-451a + miR-21-5p	0.950	0.901–0.999	95.00	81.80	0.768	–