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Observed and model-predicted percentage of patients with ulcerative colitis (UC) who achieved efficacy endpoints at maintenance Week 52. The dots and error bars represent the median and 95% confidence interval (CI) of observed NRI response by quartile of upadacitinib Cavg; solid lines and shaded areas represent the median and 95% CIs for model-predictions; boxplots represent the spread of exposure for different doses. NRI, nonresponder imputation
