Table 2.
Urinary phloroglucinol (1,3,5-trimethoxybenzene) concentration and elimination in the 0–6 h post-dose time interval
| Treatment | 1,3,5-Trihydroxybenzene | ||
|---|---|---|---|
| Concentration (ng/mL) | Elimination (mg) | Elimination (%) | |
| Test A—i.v. (40 mg) No deconjugation | 1740.88 ± 1528.76 (87.82) | 1.12 ± 0.49 (44.07) | 2.79 ± 1.23 (44.07) |
| Test A—i.v. (40 mg) After deconjugation | 43,881.25 ± 23,656.13 (53.91) | 30.78 ± 7.03 (22.85) | 76.94 ± 17.58 (22.85) |
| Test B—p.o. (160 mg) No deconjugation | 2076.88 ± 1705.63 (82.12) | 1.33 ± 0.63 (47.15) | 0.83 ± 0.39 (47.15) |
| Test B—p.o. (160 mg) After deconjugation | 136,041.67 ± 64,117.61 (47.13) | 128.90 ± 30.79 (23.89) | 80.57 ± 19.24 (23.89) |
Data are presented as mean ± SD (CV%)