Pain and spasms of urinary and biliary tracts are conditions causing poor quality of life. Treatment with analgesic drugs such as non-steroidal anti-inflammatory drugs and modulators of the parasympathetic system are not always tolerated, and additional therapeutic options are necessary.

We analysed four phase 3 multicentre, open-label, randomized, comparative studies of clinical effectiveness and safety in patients with pain and spasms of urinary or biliary tracts.

Oral and parenteral preparations based on phloroglucinol are as effective in reducing pain and spasms associated with renal or biliary colic as current therapeutic options.