Table 2.
Bile leakage documentation
| Bile leakage documentation | Cohort (n = 576) | Major resection (n = 269) | Minor resection (n = 307) | p-value | |
|---|---|---|---|---|---|
| Bile leakage ISGLS (type A–C) | 109 (18.9%) | 65 (24.1%) | 44 (14.3%) | 0.003 | |
| Bile leakage ISGLS (type B/C) | 96 (16.5%) | 56 (20.8%) | 40 (13.0%) | 0.02 | |
| White test | 157 (27.3%) | 113 (42.0%) | 44 (14.3%) | < 0.001 | |
| Intraoperative bile leakage | 85 (14.8%) | 63 (23.4%) | 22 (7.1%) | < 0.001 | |
| Drain | 442 (76.7%) | 231 (85.9%) | 211 (68.7%) | < 0.001 | |
| Day 1 | Bilirubin S/D ratio | 19.5 ± 36.9 | 26.5 ± 44.8 | 10.5 ± 23.7 | |
| Drain removed | 9 (2.0%) | 4 (1.7%) | 5 (2.3%) | 0.28 | |
| Stenting/drain | 3 (0.5%) | 3 (1.1%) | 0 | 0.06 | |
| Macro. bile in drain or wounds? | 12 (2.1%) | 8 (2.9%) | 4 (1.3%) | 0.17 | |
| Day 2 | Bilirubin S/D ratio | 5.5 ± 13.7 | 6.0 ± 17.3 | 4.1 ± 3.5 | 0.41 |
| Drain removed | 45 (7.8%) | 24 (10.3%) | 21 (9.9%) | 0.27 | |
| Stenting/drain | 6 (1.0%) | 5 (2.1%) | 1 (0.3%) | 0.07 | |
| Macro. bile in drain or wounds? | 20 (3.5%) | 14 (5.2%) | 6 (1.9%) | 0.03 | |
| Day 3 | Bilirubin S/D ratio | 3.6 ± 8.9 | 3.1 ± 9.0 | 4.2 ± 8.9 | 0.07 |
| Drain removed | 170 (29.5%) | 99 (42.9%) | 71 (33.6%) | 0.01 | |
| Stenting/drain | 6 (1.0%) | 4 (1.4%) | 2 (0.6%) | 0.32 | |
| Macro. bile in drain wounds? | 33 (5.7%) | 23 (8.5%) | 10 (3.2%) | 0.006 | |
| Day 4 | Bilirubin S/D ratio | 3.4 ± 9.6 | 4.3 ± 12.1 | 2.3 ± 4.9 | 0.33 |
| Drain removed ≥ day4 | 147 (25.5%) | 89 (38.5%) | 58 (27.5%) | 0.19 | |
| Stenting/drain | 6 (1.0%) | 6 (2.2%) | 0 | 0.04 | |
| Macro. bile in drain or wounds? | 28 (4.9%) | 19 (7.0%) | 9 (2.9%) | 0.02 | |
| > Day 4 | Bilirubin S/D ratio > day 4 | 4.7 ± 9.7 | 4.6 ± 9.9 | 5.0 ± 9.5 | 0.80 |
| Stenting/drain | 55 (9.5%) | 30 (11.1%) | 25 (8.1%) | 0.13 | |
| Drain longer than 7 days in situ | 82 (14.2%) | 51 (18.9%) | 31 (10.1%) | 0.002 | |
| Reoperation for bile leakage | 12 (2.1%) | 9 (3.3%) | 3 (0.9%) | 0.02 | |