Table 2.

Correlates of delayed treatment (with and without type of first HCC treatment)

	Delayed treatment (without first HCC treatment) n=8450 OR (95% CI)1	Delayed treatment (with first HCC treatment) n=8450 OR (95% CI)2
Age at diagnosis
65 – 69 years	Ref	Ref
70 – 74 years	0.94 (0.80,1.10)	0.95 (0.81,1.12)
75 – 79 years	0.71 (0.59,0.85)	0.72 (0.60,0.86)
80 years and older	0.78 (0.65,0.95)	0.77 (0.63,0.93)
Male sex	1.03 (0.90,1.17)	1.02 (0.89,1.16)
Race and ethnicity
White	Ref	Ref
Black	1.91 (1.20,3.05)	1.96 (1.21,3.15)
Asian	1.27 (0.96,1.68)	1.30 (0.98,1.72)
Hispanic	1.02 (0.53,1.97)	1.02 (0.53,1.96)
Other/Unknown	1.01 (0.70,1.45)	1.02 (0.71,1.45)
Neighborhood-level SES
Affluent neighborhoods	Ref	Ref
Moderate poverty neighborhoods	1.30 (1.08,1.57)	1.29 (1.07,1.55)
Poor neighborhoods	1.53 (1.24,1.89)	1.55 (1.25,1.92)
Interaction of race, ethnicity, and poverty
Black#Moderate poverty neighborhoods	0.72 (0.40,1.32)	0.71 (0.39,1.32)
Black#High poverty neighborhoods	0.61 (0.34,1.08)	0.59 (0.33,1.06)
Asian#Moderate poverty neighborhoods	0.82 (0.54,1.25)	0.82 (0.54,1.26)
Asian#High poverty neighborhoods	0.44 (0.26,0.74)	0.44 (0.26,0.73)
Hispanic#Moderate poverty neighborhoods	1.63 (0.72,3.69)	1.58 (0.70,3.58)
Hispanic#High poverty neighborhoods	0.83 (0.37,1.85)	0.82 (0.37,1.83)
Geographic region
West	Ref	Ref
Northeast	1.05 (0.88,1.26)	1.07 (0.89,1.28)
Midwest	0.83 (0.66,1.05)	0.82 (0.65,1.04)
South	0.65 (0.54,0.79)	0.65 (0.54,0.79)
Metropolitan status
Metro > 1 million	Ref	Ref
Metro 250,000 – 1 million	1.10 (0.94,1.28)	1.10 (0.94,1.29)
Metro <250,000	1.29 (1.01,1.65)	1.29 (1.00,1.66)
Non-Metro	0.87 (0.69,1.09)	0.88 (0.69,1.11)
Tumor Staging
Unifocal <=5 cm without vascular invasion and metastasis	Ref	Ref
Beyond unifocal without vascular invasion and metastasis	1.00 (0.86,1.16)	0.95 (0.81,1.11)
Vascular invasion or metastasis	0.89 (0.60,1.32)	0.83 (0.55,1.26)
NCI comorbidity index
0	Ref	Ref
1	0.93 (0.76,1.15)	0.92 (0.75,1.14)
2	1.05 (0.86,1.29)	1.01 (0.82,1.24)
3	1.18 (0.96,1.45)	1.12 (0.91,1.38)
4	1.35 (1.02,1.78)	1.31 (0.99,1.73)
>=5	1.06 (0.84,1.34)	1.01 (0.80,1.28)
Liver disease etiology
HCV	Ref	Ref
HBV	0.74 (0.55,1.01)	0.79 (0.58,1.07)
Alcohol related liver disease	1.02 (0.81,1.27)	1.00 (0.80,1.24)
Other liver diseases	0.99 (0.64,1.54)	1.02 (0.66,1.57)
MAFLD	0.81 (0.68,0.95)	0.85 (0.72,1.00)
No identifiable liver disease	0.87 (0.69,1.09)	0.92 (0.73,1.15)
Liver dysfunction
Presence of hepatic encephalopathy	0.88 (0.68,1.15)	0.82 (0.63,1.07)
Presence of ascites	0.89 (0.72,1.10)	0.86 (0.70,1.07)
First HCC treatment type
Liver transplantation		1.24 (0.82,1.87)
Surgical resection		0.38 (0.29,0.49)
Local ablation		0.81 (0.68,0.98)
Embolization		Ref
Systemic chemotherapy		0.81 (0.69,0.96)
Radiation		0.90 (0.68,1.20)

¹Model included year fixed effects (not reported)

²Model included year fixed effects (not reported)