Table 5.
Demographic variables, means (SD) on commonly administered neuropsychological tests, and mean (SD) numbers of autocorrect errors produced by participants with Probable AD and case control matched cognitively normal and biomarker negative participants (four males and four females in each group).
| Normal & Biomarker − (n=8) |
Probable AD (n=8) | ||||
|---|---|---|---|---|---|
| M | SD | M | SD | p-value | |
| Age in years | 77.0 | 5.5 | 76.1 | 9.8 | .829 |
| Education level in years | 17.0 | 1.8 | 16.9 | 2.7 | .914 |
| DRS (/144) | 139.4 | 4.1 | 127.4 | 9.3 | .005 |
| CVLT II Trials 1-5 | 55.1 | 11.7 | 32.8 | 8.4 | <.001 |
| CVLT LDFR | 12.0 | 3 | 2.9 | 3.1 | <.001 |
| Letter Fluency (FAS) | 49.2 | 14.6 | 39.5 | 13.8 | .191 |
| Semantic Fluency | 52.1 | 7.0 | 29.4 | 13.5 | <.001 |
| MINT | 31.5 | 1.1 | 29.8 | 1.7 | .026 |
| Autocorrect task | |||||
| Function dominant | 2.1 | 1.1 | 5.3 | 2.4 | .005 |
| Function nondominant | 1.6 | 1.3 | 2.9 | 1.9 | .145 |
| Content dominant | 0.9 | 1.1 | 1.4 | 1.5 | .464 |
| Content nondominant | 0.5 | 0.5 | 2.0 | 1.9 | .045 |
| All Errors | 5.1 | 1.8 | 11.5 | 6.6 | .020 |
| Paragraph Reading Times | 82.4 | 9.1 | 89.9 | 14.5 | .240 |
Note:
***
p < .001
**
p < .01
*
p < .05 Group differences significant at p < .05 are bolded based on an independent samples t-test. DRS = Dementia Rating Scale; CVLT = California Verbal Learning Test; LDFR = Long Delay Free Recall; MINT = Multilingual Naming Test (32 item UDS NACC version); Semantic Fluency is the sum of Animals and Vegetables.