Table 2:
Inflammatory protein expression in non-ischemic myocardium of EV-treated swine
| Protein | Median (IQR) | P Value |
|---|---|---|
|
| ||
| Pro-Inflammatory | ||
| NFκB | 0.73 (0.70–0.91) | 0.03 |
| Pro-IL1β | 1.04 (0.82–1.28) | 0.95 |
| IL-6 | 0.85 (0.73–1.15) | 0.85 |
| TNF-α | 0.89 (0.76–0.97) | 0.35 |
| Anti-Inflammatory | ||
| IL-10 | 1.02 (0.88–1.22) | 0.57 |
| NFκβ Regulator | ||
| IKB-α | 0.92 (0.85–0.96) | 0.11 |
Statistics presented as median fold change (interquartile range) in extracellular vesicle (EV) treated swine (n=8) compared to average control (n=6). P values calculated using Wilcoxon rank-sum test.