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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2022 Aug 4;165(5):e225–e236. doi: 10.1016/j.jtcvs.2022.07.016

Table 2:

Inflammatory protein expression in non-ischemic myocardium of EV-treated swine

Protein Median (IQR) P Value

Pro-Inflammatory
NFκB 0.73 (0.70–0.91) 0.03
Pro-IL1β 1.04 (0.82–1.28) 0.95
IL-6 0.85 (0.73–1.15) 0.85
TNF-α 0.89 (0.76–0.97) 0.35
Anti-Inflammatory
IL-10 1.02 (0.88–1.22) 0.57
NFκβ Regulator
IKB-α 0.92 (0.85–0.96) 0.11

Statistics presented as median fold change (interquartile range) in extracellular vesicle (EV) treated swine (n=8) compared to average control (n=6). P values calculated using Wilcoxon rank-sum test.