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. 2023 Jan 13;55(1):215–227. doi: 10.1038/s12276-023-00925-1

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© The Author(s) 2023, corrected publication 2023

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Fig. 8 — Monocytes express melatonin receptors in the BM and the circulation. However, monocytes lose this expression after infiltrating the CNS and differentiating into macrophages. On the other hand, microglia, and brain-resident macrophages express melatonin receptors, while BM-derived macrophages lack this expression in demyelinated mice.