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. 2022 May 18;7(3):365–374. doi: 10.1182/bloodadvances.2021006281

Table 3.

Nonelderly (0-64 yr of age) lifetime total costs and OOP costs attributable to SCD and their decomposition into costs due to the intensity and mortality effects

Sex LE (0-64), yr (SCD vs Matched Controls) Survival-adjusted Costs for SCD Individuals (95% CI) Survival-adjusted Costs for Matched Controls (95% CI) SCD-attributable Costs (95% CI) SCD-attributable Intensity Effect (95% CI) SCD-attributable Mortality Effect (95% CI)
Total Costs, $
 Females 51.2 vs 62.3 1 812 743 (1 489 450 to 2 136 036) 224 623 (191 989 to 257 256) 1 588 120 (1 262 183 to 1 914 057) 1 644 900 (1 319 718 to 1 970 082) −56 780 (−85 270 to −28 290)
 Males 50.5 vs 60.3 1 937 966 (1 612 327 to 2 263 605) 189 133 (154 174 to 224 093) 1 748 832 (1 420 634 to 2 077 031) 1 792 774 (1 465 038 to 2 120 511) −43 942 (−75 860 to −12 023)
OOP Costs, $
 Females 51.2 vs 62.3 67 003 (60 597 to 73 409) 24 609 (21 084 to 28 134) 42 395 (34 756 to 50 033) 48 562 (41 264 to 55 861) −6 168 (−9 198 to −3 138)
 Males 50.5 vs 60.3 67 897 (60 696 to 75 098) 22 806 (18 479 to 27 132) 45 091 (36 491 to 53 691) 50 346 (42 005 to 58 686) −5 254 (−9 188 to −1 320)

LE, life expectancy.