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. 2022 Dec 30;299(2):102848. doi: 10.1016/j.jbc.2022.102848

Table 1.

K_M, k_cat, k_cat/K_M, and k_rel values for CRAT and CROT with various acyl-CoA substrates

Acyl-CoA	CROT				CRAT
Acyl-CoA	K_M (μM)	k_cat (s⁻¹)	k_cat/K_M (μM⁻¹ s⁻¹)	k_rel	K_M (μM)	k_cat (s⁻¹)	k_cat/K_M (μM⁻¹ s⁻¹)	k_rel
Acetyl-CoA	77	1.4	0.02	1.0	25	49	2.0	1.0
Propionyl-CoA	49	8.4	0.17	9.4	50	77	1.5	0.75
Butyryl-CoA	41	10	0.24	13	58	66	1.1	0.55
Hexanoyl-CoA	60	18	0.30	17	55	47	0.9	0.44
Octanoyl-CoA	24	13	0.54	30	21	35	1.7	0.85

k_rel calculated by dividing k_cat/K_M (acyl-CoA, CRAT or CROT) by k_cat/K_M (acetyl-CoA, CRAT or CROT).