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. 2022 Dec 31;299(2):102857. doi: 10.1016/j.jbc.2022.102857

Figure 5.

Figure 5

A model for SOD1 functional LLPS. Pathological mutations and oxidative damage induce the transition of SOD1 from phase separation to aggregation. LLPS, liquid-liquid phase separation; SOD, superoxide dismutase.