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. 2023 Feb 3;6(2):e2254313. doi: 10.1001/jamanetworkopen.2022.54313

Figure 3. Effects of Kisspeptin (KP) on Physiological Measures of Sexual Arousal (Penile Tumescence) and Sexual Brain Activity During the Long Sexual Video Task.

Figure 3.

A, Kisspeptin administration resulted in a significant increase in penile tumescence over the course of an 8-minute sexual video compared with placebo. The maximal response occurred at 8 minutes, with KP administration increasing penile tumescence by 56% more than placebo while participants watched the long sexual video. Error bars show the SEM. B, Whole-brain analysis showing increased bilateral visual cortex and right fusiform gyrus activity by KP administration in response to the long sexual video as penile tumescence increased. Red and yellow areas show activation as penile tumescence increased during KP administration compared with placebo. Clusters are corrected for multiple comparisons (z = 2.3; P < .05 for all comparisons; n = 30). L indicates left; R, right.

aP = .002 (n = 30).