Table 2.
Cycle parameters of patients grouped according to average Gn dosage per follicle
N | Group A | Group B | Group C | P |
---|---|---|---|---|
110 | 110 | 110 | ||
Initial Gn dose (IU) | 199.89 ± 30.41 | 223.18 ± 33.30 | 243.64 ± 40.73 | < 0.01 |
Total Gn dose (IU) | 1607.44 ± 296.70 | 1952.96 ± 427.61 | 2443.64 ± 563.58 | < 0.01 |
Gn duration (days) | 9.24 ± 0.94 | 9.44 ± 1.11 | 9.97 ± 1.44 | < 0.01 |
LH on day of trigger (IU/L) | 2.42 ± 1.73 | 2.28 ± 1.45 | 2.74 ± 1.76 | 0.11 |
E2 on day of trigger (pg/ml) | 4176.34 ± 1681.63 | 3207.76 ± 1424.61 | 2452.90 ± 1154.19 | < 0.01 |
P on day of trigger (ng/ml) | 0.81 ± 0.41 | 0.82 ± 0.41 | 0.75 ± 0.43 | 0.46 |
Endometrial thickness (mm) | 10.43 ± 2.33 | 10.68 ± 2.08 | 10.63 ± 2.17 | 0.67 |
FORT | 0.98 ± 0.36 | 0.77 ± 0.23 | 0.70 ± 0.26 | < 0.01 |
FOI | 1.03 ± 0.46 | 0.90 ± 0.35 | 0.93 ± 0.39 | 0.04 |
OSI | 11.80 ± 4.31 | 7.34 ± 2.46 | 4.64 ± 2.09 | < 0.01 |
No. of oocytes | 18.52 ± 6.12 | 14.09 ± 5.04 | 10.79 ± 4.21 | < 0.01 |
No. of fertilized | 14.40 ± 5.86 | 10.68 ± 4.38 | 8.41 ± 3.92 | < 0.01 |
No. of 2PN | 11.25 ± 5.18 | 8.64 ± 4.36 | 6.46 ± 3.65 | < 0.01 |
No. of good quality embryos | 4.75 ± 3.57 | 4.21 ± 3.04 | 2.86 ± 2.09 | < 0.01 |
Gn gonadotropin, FORT follicular output rate = No. of pre-ovulatory follicles/AFC, FOI follicle-to-oocyte index = No. of oocytes retrieved/AFC, OSI ovarian sensitivity index = number of retrieved oocytes/total Gn dose × 1000; 2PN two pronuclei