Table 2.
Baseline characteristics and comorbidities based on sex in patients with idiopathic pulmonary fibrosis
| Total | Men | Women | p value | |
|---|---|---|---|---|
| (n = 21,111) | (n = 15,029) | (n = 6082) | ||
| Respiratory diseases | ||||
| COPD | 7882 (37.34%) | 6099 (40.58%) | 1783 (29.32%) | < 0.001 |
| Lung cancer | 706 (3.34%) | 618 (4.11%) | 88 (1.45%) | < 0.001 |
| Pulmonary embolism | 338 (1.60%) | 232 (1.54%) | 106 (1.74%) | 0.296 |
| Pulmonary hypertension | 315 (1.49%) | 167 (1.11%) | 148 (2.43%) | < 0.001 |
| Obstructive sleep apnoea | 65 (0.31%) | 55 (0.37%) | 10 (0.16%) | 0.017 |
| Non-respiratory diseases | ||||
| GERD | 14,953 (70.83%) | 10,495 (69.83%) | 4458 (73.30%) | < 0.001 |
| Dyslipidaemia | 13,286 (62.93%) | 9411 (62.62%) | 3875 (63.71%) | 0.136 |
| Hypertension | 12,464 (59.04%) | 8817 (58.67%) | 3647 (59.96%) | 0.083 |
| Diabetes mellitus | 9483 (44.92%) | 6977 (46.42%) | 2506 (41.20%) | < 0.001 |
| Ischaemic heart disease | 5431 (25.73%) | 4118 (27.40%) | 1313 (21.59%) | < 0.001 |
| Anxiety | 4238 (20.07%) | 2730 (18.16%) | 1508 (24.79%) | < 0.001 |
| Depression | 3142 (14.88%) | 2007 (13.35%) | 1135 (18.66%) | < 0.001 |
| Congestive heart failure | 2887 (13.68%) | 1992 (13.25%) | 895 (14.72%) | 0.005 |
| CCI | 0.001 | |||
| 0 | 577 (2.73%) | 423 (2.81%) | 154 (2.53%) | |
| 1 | 3109 (14.73%) | 2196 (14.61%) | 913 (15.01%) | |
| 2 | 4109 (19.46%) | 2887 (19.21%) | 1222 (20.09%) | |
| 3 | 3823 (18.11%) | 2642 (17.58%) | 1181 (19.42%) | |
| ≥ 4 | 9493 (44.97%) | 6881 (45.78%) | 2612 (42.95%) | |
| CCI, mean (standard deviation) | 3.67 (2.40) | 3.74 (2.48) | 3.51 (2.20) | < 0.001 |
All values are presented as number (%)
CCI Charlson comorbidity index, COPD chronic obstructive pulmonary disease, GERD gastro-oesophageal reflux disease
P values calculated by chi-square tests or Wilcoxon rank sums test