FIG. 3.

Alignment of the six 20+20 bicupin proteins (presumed OXDCs) from Streptococcus mutans (S. mut), Bacillus subtilis (B. sub1, YvrK; B. sub2, YoaN), Collybia velutipes (C. vel), Aspergillus phoenices (A. pho), and Synechocystis (Syn.) (see the text for details), showing the positions of the two conserved motifs (boxed) within each of the two domains. Residues conserved in all sequences are indicated with asterisks below the alignment; residues also conserved between the two domains are indicated with asterisks above the alignment. The A. phoenices sequence (Scelonge and Bidney, PCT patent application WO 98/42827) has been amended by insertion of an additional nucleotide at residue 344 to correct a presumed frameshift error introduced during the sequencing of this gene.