FIG. 5.

Alignment of the two 20+20 bicupin genes yoaN (gi|2634260, denoted 4260) and yvrK (gi|2635821, denoted 5821) from B. subtilis, showing the positions of the two conserved motifs within each of the two domains. Similar nucleotides are shown as dots, and deletions are shown as dashes. The deletions marked with asterisks in motif 1 of the first domain (1-bp deletion) and motif 2 of the second domain (2-bp deletion) denote two examples of the compensatory system of deletions and insertions that maintain the same reading frame for the two genes throughout the majority of the sequence. The deletions which produce a respective difference in the presence of a Gly residue (Fig. 3) are marked with vertical arrowheads. The statistical analysis is as follows: score = 1,706 (256.0 bits), expect = 2.2e-72, P = 2.2e-72, identities = 756/1,151 (65%).